Management of Vitamin B12 Deficiency

People who are low in vitamin B12 and able to absorb the vitamin can increase B12 intake through a combination of eating foods rich in vitamin B12 and by taking over-the-counter vitamin supplements to successfully normalize their B12 levels.  However, there are many people who have a condition in which there is an impaired ability to absorb vitamin B12, including pernicious anemia, Crohn’s disease, celiac disease and Irritable Bowel Syndrome (IBS). Difficulties absorbing B12 also can occur with long term use of proton pump inhibitors (PPIs), a commonly used type of treatment to reduce acid in the stomach. [i]

The current treatment standard for diagnosed vitamin B12 deficiency in cases where there is an impaired capacity to absorb the vitamin is a monthly intramuscular (IM) injection. It is estimated that between 30 and 40 million high-dose injections of B12 are given each year in the U.S. and that more than 250 million such injections are given worldwide.vii

Eligen B12™ is a once-daily oral solution indicated for the dietary management of patients who have a diagnosed vitamin B12 deficiency, associated with a disease or condition, that cannot be managed by a modification of the normal diet alone. Eligen B12 uses innovative technology to enable vitamin B12 absorption orally without the need for a monthly injection, the current treatment standard for people with medically diagnosed B12 deficiency.


[i] Emisphere website. Accessed November 2014.